Masanori Miwa Selected Research

5-vinyluracil

9/2003	Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889.
3/2003	Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

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Masanori Miwa Research Topics

Disease

7	Neoplasms (Cancer) 11/2021 - 03/2003
1	Schizophrenia (Dementia Praecox) 10/2018
1	Sarcoma (Soft Tissue Sarcoma) 11/2017
1	Breast Neoplasms (Breast Cancer) 01/2010
1	Diarrhea 01/2010
1	Colorectal Neoplasms (Colorectal Cancer) 09/2003

Drug/Important Bio-Agent (IBA)

3	Pharmaceutical PreparationsIBA 10/2018 - 04/2007
3	ProdrugsIBA 01/2010 - 03/2003
3	Capecitabine (Xeloda)FDA Link 01/2010 - 03/2003
2	Peptides (Polypeptides)IBA 11/2017 - 07/2017
2	EnzymesIBA 11/2017 - 03/2003
2	5-vinyluracilIBA 09/2003 - 03/2003
2	2',3'- O- diacetyl- 5'- deoxy- 5- vinylcytidineIBA 09/2003 - 03/2003
2	Fluorouracil (Carac)FDA LinkGeneric 09/2003 - 03/2003
2	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 09/2003 - 03/2003
1	ras ProteinsIBA 07/2017
1	Amino Acids FDA Link 07/2017
1	Irinotecan (Camptosar)FDA LinkGeneric 01/2010
1	Cetuximab (Erbitux)FDA Link 01/2010
1	Cholinergic Agents (Cholinergics)IBA 01/2010
1	Bevacizumab (Avastin)FDA Link 01/2010
1	CamptothecinIBA 01/2010
1	Cisplatin (Platino)FDA LinkGeneric 01/2010
1	Proteins (Proteins, Gene)FDA Link 01/2010
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2010
1	DipeptidesIBA 04/2007
1	2'-deoxy-2'-methylenecytidineIBA 04/2007
1	DNA (Deoxyribonucleic Acid)IBA 04/2007
1	dipeptidaseIBA 04/2007
1	Complementary DNA (cDNA)IBA 09/2003
1	eniluracilIBA 09/2003
1	Thymidine PhosphorylaseIBA 03/2003
1	Cytidine DeaminaseIBA 03/2003
1	EsterasesIBA 03/2003

Therapy/Procedure

4	Therapeutics 11/2021 - 03/2003